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Cayman sPLA2 (Type X) Inhibitor Screening Assay Kit
NETA PART: | CAYM-702480-384 |
MFG.PART: | 702480-384 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Cayman’s sPLA2 (Type X) Inhibitor Screening Assay Kit provides a robust and easy-to-use platform for identifying novel inhibitors of human sPLA2 (Type X), a phospholipase that hydrolyzes PE and PC at the sn-2 position. The assay uses a sulfur-containing analog of 1,2-diheptanoyl-sn-glycero-3-PC (di-C7-PC) as a substrate. Upon hydrolysis by sPLA2 (Type X) at the sn-2 position, free thiols can be detected by the sPLA2 Assay Probe resulting in a product that can be easily quantified using its absorbance at a wavelength of 410 nm. The potent and reversible sPLA2 (Type X) inhibitor, sPLA2 Control Inhibitor, also known as LY315920 or varespladib, is included as a positive control and inhibits the enzyme with an IC50 value of approximately 11 nM.
Needed but not supplied:Please download the kit booklet to verify if UltraPure Water (Milli-Q or equivalent) or any other components are needed for this assay.
WARNING This product is not for human or veterinary use.
Technical Information
- GXsPLA2
- Phosphatidylcholine 2-Acylhydrolase 10
- PLA2G10
- Secretory Phospholipase A2 (Group 10)
- Secretory Phospholipase A2 (Group X)
- Secretory Phospholipase A2 (mouse Group X)
- Secretory Phospholipase A2 (Type X)
- sPLA2-X
Shipping & Storage Information
SKU | CAYM-702480-384 |
---|---|
Supplier Part Number | 702480-384 |
UM | EA |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/702480m.pdf |
Temperature | -80 |
Refrigerated-Frozen | Frozen |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | Y |