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Cayman Transglutaminase Activity Assay Kit
NETA PART: | CAYM-702250-96 |
MFG.PART: | 702250-96 |
UNSPSC: | 60104007 |
Manufacturer: | Cayman |
Product Description
Thiothixene is a typical antipsychotic. It selectively binds to dopamine D2 over D1, D3, and D4 receptors (Kis = 0.417, 338, 186.2, and 363.1 nM, respectively). Thiothixene also binds to various serotonin (5-HT), histamine H1, α1- and α2-adrenergic, muscarinic acetylcholine, and sigma receptors (Kis = 15-5,754 nM) as well as the dopamine, norepinephrine, and serotonin transporters (Kis = 3.16-30 μM). In vivo, thiothixene reduces spontaneous and amphetamine-induced locomotor activity in rats. It enhances latent inhibition, as measured by a decreased lick latency in response to light and foot shock stimuli, which is a measure of selective attention in rats. Thiothixene also increases competitive behavior in submissive mice, indicating antidepressant-like behavior. Formulations containing thiothixene have been used in the treatment of schizophrenia and bipolar mania.
WARNING This product is not for human or veterinary use.
Technical Information
- CP 12,252-1
- NSC 108165
- P 4657B
- cis-Thiothixene
- DMF: 0.5 mg/ml
- DMSO: 0.2 mg/ml
Shipping & Storage Information
SKU | CAYM-702250-96 |
---|---|
Supplier Part Number | 702250-96 |
UM | EA |
UNSPSC | 60104007 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/702250m.pdf |
Temperature | -80 |
Refrigerated-Frozen | Frozen |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | Y |