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Cayman DXR Inhibitor 11a (sodium salt)
Cayman DXR Inhibitor 11a (sodium salt) - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$152.00
Your Price
$152.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-39305-1 |
| MFG.PART: | 39305-1 |
| UNSPSC: | 12352100 |
| Manufacturer: | Cayman |
Product Description
Farnesoid X receptor (FXR) is a nuclear receptor that acts as a bile acid sensor, protecting cells and organs against bile acid toxicity. GW 4064 is a selective agonist of FXR (EC50 = 15 nM). It displays no activity at other nuclear receptors, including the retinoic acid receptor, at concentrations up to 1 μM. GW 4064 is used to elucidate the role of FXR in dyslipidemia, diabetes, obesity, and cancer.,,,,
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
3-
CAS Number
278779-30-9
Molecular Formula
C28H22Cl3NO4
Formula Weight
542.8
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 25 mg/ml
- DMSO: 25 mg/ml
- DMSO:PBS(pH 7.2) (1:2): 0.3 mg/ml
- Ethanol: 1 mg/ml
λmax
304 nm
SMILES
ClC(C=CC=C1Cl)=C1C2=NOC(C(C)C)=C2COC(C=C3)=CC(Cl)=C3/C=C/C4=CC(C(O)=O)=CC=C4
InChi Code
InChI=1S/C28H22Cl3NO4/c1-16(2)27-21(26(32-36-27)25-22(29)7-4-8-23(25)30)15-35-20-12-11-18(24(31)14-20)10-9-17-5-3-6-19(13-17)28(33)34/h3-14,16H,15H2,1-2H3,(H,33,34)/b10-9+
InChi Key
BYTNEISLBIENSA-MDZDMXLPSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-39305-1 |
|---|---|
| Supplier Part Number | 39305-1 |
| UM | EA |
| UNSPSC | 12352100 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/39305m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | Y |