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Cayman Thioredoxin Reductase 1 (human, recombinant)
Cayman Thioredoxin Reductase 1 (human, recombinant) - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$638.00
Your Price
$638.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-39624-200 |
MFG.PART: | 39624-200 |
UNSPSC: | 12352202 |
Manufacturer: | Cayman |
Product Description
HPOB is a potent inhibitor of histone deacetylase 6 (HDAC6; IC50 = 56 nM). It is at least 30-fold less effective against other HDACs. Through its effects on HDAC6, HPOB induces acetylation of α-tubulin but not histones. HPOB reduces the growth, but not the viability, of normal and transformed cells. It enhances the death of transformed cells as triggered by the topoisomerase II inhibitors etoposide and doxorubicin. HPOB enhances the cytotoxicity of the broad spectrum HDAC inhibitor SAHA (Item No. ) against cancer cells in nude mice carrying an androgen-dependent CWR22 human prostate cancer xenograft.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-[(hydroxy amino) carbonyl]-N- (2-hydroxy ethyl)-N- phenyl-benzene acetamide
CAS Number
1429651-50-2
Molecular Formula
C17H18N2O4
Formula Weight
314.3
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 10 mg/ml
- DMSO: 20 mg/ml
- DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
- Ethanol: 15 mg/ml
λmax
235 nm
SMILES
OCCN(C(CC1=CC=C(C(NO)=O)C=C1)=O)C2=CC=CC=C2
InChi Code
InChI=1S/C17H18N2O4/c20-11-10-19(15-4-2-1-3-5-15)16(21)12-13-6-8-14(9-7-13)17(22)18-23/h1-9,20,23H,10-12H2,(H,18,22)
InChi Key
RFAZNTABYJYOAR-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
SKU | CAYM-39624-200 |
---|---|
Supplier Part Number | 39624-200 |
UM | EA |
UNSPSC | 12352202 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/39624m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | SE |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |