Revvity LabChip AAV Protein Analysis Kit

Fast, Automated Analysis of AAV Protein:

The LabChip AAV Protein Analysis kit is one component of the LabChip AAV Protein Analysis Assay. It provides on-chip labeling and detection of AAV viral proteins. AAV samples with as little as 5 µL may be analyzed with an electrophoresis run-time of 42 s per sample. Nov-covalent labeling with the increased plug-pinch size is incorporated to allow easy sample analysis for AAV samples with a concentration of 1E12 VP/mL.

Protein Detection for Empty/Full Analysis:

The LabChip AAV Protein Analysis Assay automates AAV Empty/Full determination when used in combination with the LabChip AAV DNA Analysis Assay. The software includes data analysis for AAV Empty/Full determination using referencing measurements to an AAV standard (sold separately).

Viral Protein Characterization:

In addition to empty/full measurement, measurement of AAV capsid purity and viral protein stoichiometry is critical to AAV development. The LabChip AAV Protein Analysis Assay provides electropherogram data including peak arrival time, size, and concentration in addition to AAV-specific metrics of viral protein stoichiometry.

This assay is compatible with the LabChip GXII Touch Protein Characterization System.

Note: LabChip Software version 1.13 and LabChip Reviewer Software version 5.11 or higher are needed for AAV Empty/Full Analysis

Consumables needed for the Empty/Full AAV Protein Analysis Assay*:

• AAV Protein Analysis Kit (CLS157462)
• AAV Empty/Full Protein LabChip (CLS157612)
• AAV8 Standard (CLS157467)

*Used for Empty/Full Analysis along with AAV DNA Analysis Assay and LabChip GXII Touch Protein Characterization System