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GenScript MMAE ADC Pharmacokinetic ELISA Kit
GenScript MMAE ADC Pharmacokinetic ELISA Kit - GSCRPT (Additional S&H or Hazmat Fees May Apply)
List Price
$498.00
Your Price
$498.00
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NETA PART: | GSCRPT-L00991 |
MFG.PART: | L00991 |
UNSPSC: | 41116126 |
Manufacturer: | GenScript USA Inc |
GenScript Monomethyl auristatin E (MMAE) is a synthetic antineoplastic agent. It inhibits cell division by blocking the polymerisation of tubulin.It is linked to a monoclonal antibody as a payload in MMAE conjugated antibody drug (MMAE-ADC) development [1-3]. There are several FDA approved MMAE-ADC drugs, such as Disitamab vedotin, Tivdak, Padcev, Polivy and Adcetris. MMAE-ADC can activate the antimitotic mechanism by cathepsin cleavage after it has entered a tumor cell, thus [4].
GenScript has comprehensively developed and validated the MMAE ADC Pharmacokinetic ELISA Kit for the quantitative measurement of MMAE-ADC in cynomolgus monkeyserum and plasma. This kit is based on the ICH M10 and the FDA bioanalytical method validation guidance for industry, ensuring its precision, accuracy, dilutional linearity, specificity, selectivity, stability, and hook effect were acceptable [5-8]. The ELISA kit is a validated tool for MMAE-ADC quantification in biological matrices for drug research and development. - GSCRPT (Additional S&H or Hazmat Fees May Apply)
GenScript has comprehensively developed and validated the MMAE ADC Pharmacokinetic ELISA Kit for the quantitative measurement of MMAE-ADC in cynomolgus monkeyserum and plasma. This kit is based on the ICH M10 and the FDA bioanalytical method validation guidance for industry, ensuring its precision, accuracy, dilutional linearity, specificity, selectivity, stability, and hook effect were acceptable [5-8]. The ELISA kit is a validated tool for MMAE-ADC quantification in biological matrices for drug research and development.
SKU | GSCRPT-L00991 |
---|---|
Supplier Part Number | L00991 |
UM | EA |
UNSPSC | 41116126 |
Manufacturer | GenScript USA Inc |
ProductLine | GSCRPT |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 7 Business Days |
Hazardous | Y |