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GenScript TGFB1, Bovine
GenScript TGFB1, Bovine - GSCRPT (Additional S&H or Hazmat Fees May Apply)
List Price
$683.00
Your Price
$683.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | GSCRPT-Z03779-100 |
MFG.PART: | Z03779-100 |
UNSPSC: | 12352202 |
Manufacturer: | GenScript USA Inc |
GenScript TGF-B1 (transforming growth factor beta 1) is one of three closely related mammalian members of the large TGF-B1 superfamily that share a characteristic cystine knot structure. TGF-B1, -2 and -3 are highly pleiotropic cytokines that act as cellular switches to regulate processes such as immune function, proliferation and epithelial-mesenchymal transition. Each TGF-B isoform has some non-redundant function; for TGF-B1, mice with targeted deletion show defects in hematopoiesis and endothelial differentiation and died of overwhelming inflammation. TGF-B1 signaling begins with high-affinity binding to a type II ser/thr kinase receptor termed TGF-B RII. This receptor then phosphorylates and activates a second ser/thr kinase receptor, TGF-B RI (also called activin receptor‑like kinase (ALK)-5), or alternatively, ALK-1. This complex phosphorylates and activates Smad proteins that regulate transcription. - GSCRPT (Additional S&H or Hazmat Fees May Apply)
SKU | GSCRPT-Z03779-100 |
---|---|
Supplier Part Number | Z03779-100 |
UM | EA |
UNSPSC | 12352202 |
Manufacturer | GenScript USA Inc |
ProductLine | GSCRPT |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 7 Business Days |
Hazardous | N |