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Cayman Prochloraz
Cayman Prochloraz - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$96.00
Your Price
$96.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-24051-500 |
| MFG.PART: | 24051-500 |
| UNSPSC: | 12352100 |
| Manufacturer: | Cayman |
Product Description
Prochloraz is an imidazole antifungal that inhibits ergosterol biosynthesis via inhibition of the cytochrome P450-dependent 14α-demethylation of lanosterol, which results in disruption of the fungal cell membrane and cell death.1 It inhibits human placenta microsomal aromatase in vitro (IC50 = 40 nM).2 Prochloraz also acts as an antagonist of the estrogen receptor (ER) and androgen receptor (AR) (IC50s = 25 and 4 μM, respectively) as well as activates the aryl hydrocarbon receptor (AhR; EC50 = 1 μM).3 In vivo, prochloraz (250 mg/kg) reduces the weight of seminal vesicles in intact male rats and of seminal vesicles, ventral prostate, and bulbourethral glands in castrated testosterone-treated male rats.4 It also reduces testosterone levels and increases progesterone levels in male rat pups following administration of a 30 mg/kg per day dose to pregnant females during gestation.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-propyl-N-
CAS Number
67747-09-5
Synonyms
- BTS-40542
Molecular Formula
C15H16Cl3N3O2
Formula Weight
376.7
Purity
≥98%
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/ml
- DMSO: 30 mg/ml
- Ethanol: 30 mg/ml
- Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
SMILES
ClC1=C(OCCN(CCC)C(N2C=NC=C2)=O)C(Cl)=CC(Cl)=C1
InChi Code
InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3
InChi Key
TVLSRXXIMLFWEO-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-24051-500 |
|---|---|
| Supplier Part Number | 24051-500 |
| UM | EA |
| UNSPSC | 12352100 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/24051m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | CA |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | Y |
| CAS Number | 67747-09-5 |