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Cell Signaling Ppp2r2a (2g9) Mouse mAb
Cell Signaling Ppp2r2a (2g9) Mouse mAb - CSIG (Additional S&H or Hazmat Fees May Apply)
List Price
$138.00
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$138.00
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NETA PART: | CSIG-5689T |
MFG.PART: | 5689T |
UNSPSC: | 41116111 |
Manufacturer: | Cell Signaling |
Size | 20 µl |
Reactivity | H M R Mk |
Sensitivity | Endogenous |
Molecular Weight (kDa) | 52 |
Source/Isotype | Mouse IgG1 |
Application/Dilution | {Western Blotting: 1:1000, Immunoprecipitation: 1:50} |
Storage | Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody. |
Specificity/Sensitivity | PPP2R2A (2G9) Mouse mAb recognizes endogenous levels of total PPP2R2A/PP2A, B55-α/PR55-α protein. This antibody cross-reacts with overexpressed PPP2R4 and PPP2R5D proteins. |
Species Reactivity | Human, Mouse, Rat, Monkey |
Source/Purification | Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Asp406 of rat PP2R2A/PP2A, B55-α/PR55-α protein. |
Background | Protein phosphatase 2A subunit B isoform R2-α (PPP2R2A) is the component of regulatory subunit B of serine/threonine protein phosphatase 2A (PP2A). PPP2R2A belongs to the R2/B55/PR55 family of regulatory subunit B (1). Evidence suggests that subunit PPP2R2A enhances TGF-β, Activin, and Nodal signaling pathways (7) and may play an important role in cell cycle regulation (2-4). PPP2R2A/PP2A, B55-α/PR55-α isoform interacts with the type I TGF-β receptors via unique WD-40 repeats (5) that contribute to the anti-proliferative function of TGF-β receptors (6). |
SKU | CSIG-5689T |
---|---|
Supplier Part Number | 5689T |
UM | UNIT |
UNSPSC | 41116111 |
Manufacturer | Cell Signaling |
MSDS URL | https://www.cellsignal.com/contents/technical/safety-data-sheet-(sds)/resources-safety-data-sheets |
Temperature | -20C |
ProductLine | CSIG |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 5 Business Days |