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Key Specifications Table
| Species Reactivity | Key Applications | Host | Format | Antibody Type |
|---|---|---|---|---|
| H, R, M | ICC, IHC, IF, IH(P) | M | Purified | Monoclonal Antibody |
| Description | |
|---|---|
| Catalogue Number | MAB2300 |
| Trade Name |
|
| Description | Milli-Mark™ Pan Neuronal Marker |
| Background Information | Antibodies to neuronal proteins have become critical tools for identifying neurons and discerning morphological characteristics in culture and complex tissue. While the labeling from classic histological techniques such as Golgi staining and modern molecular approaches such as GFP constructs yield excellent cytoarchitectural detail, these approaches are technically challenging and impractical for many neuroscience research needs. Neuron-specific antibodies are convenient precision tools useful in revealing cytoarchitecture, but are limited to the protein target distribution within the neuron, which may differ greatly from nucleus to soma to dendrite and axon. To achieve as complete a morphological staining as possible across all parts of neurons, Millipore has developed a monoclonal antibody blend that reacts against key somatic, nuclear, dendritic, and axonal proteins distributed across the pan-neuronal architecture that can then be detected by a single secondary antibody. This antibody cocktail has been validated in diverse fixations, cell culture and immunohistochemistry protocols, including archival brain tissue, giving researchers a convienent and specific qualitative and quantitative tool for studying neuronal morphology. |
| Product Information | |
|---|---|
| Format | Purified |
| Control |
|
| Presentation | Blended monoclonal antibody cocktail in PBS with 0.05% NaN3 |
| Quality Level | MQ100 |
| Applications | |
|---|---|
| Application | Milli-Mark Pan Neuronal Marker is an antibody targeting the Pan Neuronal Marker protein, validated for use in ICC, IHC, IF & IHC. |
| Key Applications |
|
| Biological Information | |
|---|---|
| Epitope | Whole Neuron Marker |
| Host | Mouse |
| Specificity | Cat. # MAB2300 is specific to axons (neurites), dendrites, nucleus, and the cell body of neurons. |
| Isotype | IgG1 |
| Species Reactivity |
|
| Species Reactivity Note | Rat, Mouse and Human. Reactivity with other species has not been determined. |
| Antibody Type | Monoclonal Antibody |
| Product Usage Statements | |
|---|---|
| Quality Assurance | Routinely tested Rat E18 cortex primary neurons in Immunocytochemistry. |
| Usage Statement |
|
| Storage and Shipping Information | |
|---|---|
| Storage Conditions | Maintain at 2-8°C for up to 1 year from date of receipt. |
| Packaging Information | |
|---|---|
| Material Size | 100 µL |