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Genscript IL-12, Mouse
Genscript IL-12, Mouse - GSCRPT (Additional S&H or Hazmat Fees May Apply)
List Price
$3,564.75
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$3,564.75
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| NETA PART: | GSCRPT-Z03211-1 |
| MFG.PART: | Z03211-1 |
| UNSPSC: | 12350000 |
| Manufacturer: | GenScript USA Inc |
Product Introduction
| Species | Mouse | ||
| Protein Construction |
| ||
| Purity | > 95% as analyzed by SDS-PAGE | ||
| Endotoxin Level | < 0.2 EU/μg of protein by gel clotting method | ||
| Biological Activity | ED50 < 0.15 ng/ml, measured in a cell proliferation assay using 2D6 cells. | ||
| Expression System | CHO | ||
| Apparent Molecular Weight | 27~29 kDa (p35), 45~50 kDa (p40), on SDS-PAGE under reducing conditions. | ||
| Formulation | Lyophilized after extensive dialysis against PBS. | ||
| Reconstitution | It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O or PBS up to 100 μg/ml. | ||
| Storage & Stability | Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles. |
Background
| Target Background | Interleukin-12 (IL-12), also known as NKSF, TCMF, CLMF and TSF, is a heterodimeric cytokine composed of p35 and p40 subunits. It is produced by monocytes, macrophages, B cells and dendritic cells in response to bacterial lipopolysaccharides and intracellular pathogens. IL-12 signals throughtheIL-12 receptor complex, which is comprised of IL-12 Rβ1 and IL-12 Rβ2. IL-12 induces the proliferation and activation of hematopoietic stem cells, natural killer cells and T- cells. It is indispensible during the development of Th1 cells, leading to the production of IFN-gamma and IL-2. |
| Synonyms | IL12; NKSF; TCMF; CLMF; TSF; CTL maturation factor; Cytotoxic lymphocyte maturation factor |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
| SKU | GSCRPT-Z03211-1 |
|---|---|
| Supplier Part Number | Z03211-1 |
| UM | EA |
| UNSPSC | 12350000 |
| Manufacturer | GenScript USA Inc |
| ProductLine | GSCRPT |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 7 Business Days |
| Hazardous | N |