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Genscript Flt-3L, His, Mouse
Genscript Flt-3L, His, Mouse - GSCRPT (Additional S&H or Hazmat Fees May Apply)
List Price
$105.00
Your Price
$105.00
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| NETA PART: | GSCRPT-Z03227-10 |
| MFG.PART: | Z03227-10 |
| UNSPSC: | 12350000 |
| Manufacturer: | GenScript USA Inc |
Product Introduction
| Species | Mouse | ||||
| Protein Construction |
| ||||
| Purity | > 95% as analyzed by SDS-PAGE | ||||
| Endotoxin Level | < 0.2 EU/μg of protein by gel clotting method | ||||
| Biological Activity | ED50 < 10.0 ng /ml, measured in a cell proliferation assay using AML5 cells. | ||||
| Expression System | CHO | ||||
| Apparent Molecular Weight | 24-30 kDa, on SDS-PAGE under reducing conditions. | ||||
| Formulation | Lyophilized after extensive dialysis against PBS. | ||||
| Reconstitution | It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O or PBS up to 100 μg/ml. | ||||
| Storage & Stability | Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles. |
Background
| Target Background | Flt3L, also known as Fms-related tyrosine kinase 3 ligand and SL cytokine, is a single-pass type I membrane protein. It is expressed by stromal cells and T cells. Flt3L signals through tyrosine kinase receptor Flt3/Flk2 to stimulate the proliferation of early hematopoietic progenitor cells. It synergizes with other growth factors, such as GM-CSF, IL-3 and CSF, to promote the differentiation of both myeloid and lymphoid cells. Alternative splicing and proteolytic cleavage of membrane-bound Flt3L generates a soluble extracellular domain (ECD) isoform with full biological activity. |
| Synonyms | Flt3 ligand; Flt3LG; SL cytokine; Fms-related tyrosine kinase 3 ligand |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
| SKU | GSCRPT-Z03227-10 |
|---|---|
| Supplier Part Number | Z03227-10 |
| UM | EA |
| UNSPSC | 12350000 |
| Manufacturer | GenScript USA Inc |
| ProductLine | GSCRPT |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 7 Business Days |
| Hazardous | N |