Spectrum Chemical TRIS AMINO AC Ultra Pu

Spectrum Chemical TRIS AMINO AC Ultra Pure, USP, EP, Biologics Grade Manufactured by ANGUS Chemical Company, TRIS AMINO™ AC (Advanced Crystal) Ultra Pure buffer features a unique crystal morphology that results in less time, energy and cost to break up clumps prior to buffer preparation. TRIS AMINO AC Ultra Pure is manufactured using a proprietary process technology that produces a larger, more rounded particle. Without making any changes to the molecule itself, this process helps prevent the formation of strong, hard cakes even when subjected to a variety of packaging, shipping and storage conditions.• Low interparticle cohesion between crystals requires less energy to break up clumps• More spherical crystals for easy dispensing and transport• Fewer fine particles for lower dust emissions• No additives or anti-clumping agents• Highest purity and testing requirements including bioburden and endotoxin• cGMP-compliant with comprehensive documentation• Proven safe use in commercial drug products• Fully traceable supply chain including base materials• Elemental impurity risk assessment using ICP-MS technology• Ability to maintain pH from 7 to 9 by utilizing a combination of free base and its salts• Amine and alcohol functionality for versatile chemical reactivityUses and Applications• Pharmaceutical raw material compliant with USP, EP, JPC, and ChP monographs• Commercial purification (downstream processing) of biological molecules including monoclonal antibodies and recombinant proteins• Processing aid for insulin manufacturing• Non-sterile pharmaceutical excipient• Buffer for molecular biology and clinical diagnostic applications• pH buffering of enzymes in biotechnology applications• Small mlecule API salt to systematically adjust drug hydrophilicity• Small molecule synthesis building blockTypical Properties*Purity: 99.9%Molecular weight: 121.14Melting point: 168.0 – 172.0°CpKa at 20°C: 8.3pKa at 37°C: 7.8pKa/°C: -0.03pH of 0.1M aqueous solution (20°C): 10.4Ä pH/10X dilution: -0.05 to -0.10*Values shown are typical properties and are not to be considered product specifications. Biologics Grade is tested for bioburden and endotoxin. - SPCM (Additional S&H or Hazmat Fees May Apply)