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Protein is expressed in E.coli. The protein is manufactured without the use of any animal products/reagents and is considered Animal-Free and can be used in protocols where possible transmisson of animal viruses and contamination must be avoided.
Product endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Description
Catalogue Number
GF345
Description
SDF-1β (CXCL12), Human Recombinant Animal Free
Alternate Names
Stromal Cell-Derived Factor
CXCL12
SDF1B
TLSF-b
TPAR1
SDF-1b
TLSF
Background Information
SDF-1α and β are stromal derived CXC chemokines, and signal through the CXCR4 receptor. SDF-1α and β chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV suppressive activity in cells expressing the CXCR4 receptor. Recombinant human SDF-1β is an 8.5 kDa protein containing 72 amino acid residues.
Product Information
Presentation
Product is presented without additives and is filtered through a 0.2 micron filter before lyophilization.
Quality Level
MQ100
Biological Information
Purity
Product endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Source
Protein is expressed in E.coli. The protein is manufactured without the use of any animal products/reagents and is considered Animal-Free and can be used in protocols where possible transmisson of animal viruses and contamination must be avoided.
UniProt Number
P48061
Product Usage Statements
Quality Assurance
Determined by its ability to chemoattract human peripheral T cells activated with PHA and IL-2 using a concentration range of 20.0- 80.0 ng/ml.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions
Store at -20°C for up to 4 months from date of receipt Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein and store in working aliquots at -20°C.
