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Genscript IFN-ω, Human
Genscript IFN-ω, Human - GSCRPT (Additional S&H or Hazmat Fees May Apply)
List Price
$75.00
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$75.00
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NETA PART: | GSCRPT-Z02909-20 |
MFG.PART: | Z02909-20 |
UNSPSC: | 41105300 |
Manufacturer: | GenScript USA Inc |
Product Introduction
Species | Human | |
Protein Construction |
| |
Purity | > 97% as analyzed by SDS-PAGE > 97% as analyzed by HPLC | |
Endotoxin Level | < 1 EU/μg of protein by LAL method | |
Biological Activity | Fully biologically active when compared to standard. The ED50 as determined by a chemotaxis bioassay using human TF-1 cells is less than 0.01 ng/ml, corresponding to a specific activity of > 1.0 × 108 IU/mg. | |
Expression System | E. coli | |
Theoretical Molecular Weight | 20 kDa | |
Formulation | Lyophilized from a 0.2 μm filtered solution in PBS, pH 7.4. | |
Reconstitution | It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. | |
Storage & Stability | Upon receiving, this product remains stable for up to 6 months at -70°C or -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. Avoid repeated freeze-thaw cycles. |
Background
Target Background | Interferon-Omega (IFN-ω) coded by IFNW1 gene in human, is a number of the type I interferon family, which includes IFN-a, IFN-β, and IFN-ω. The IFNAR-1/IFNAR-2 receptor complex can help with the signal transduction, followed the antiviral or the antiproliferative actions. IFN-ω is derived from IFN-a/β and share 75% sequence with IFN-a. It has two intramolecular disulfide bonds which are crucial for activities. Mire-Sluis et al have described bioassays for IFN-α, IFN-β, and IFN-ω that exploit the ability of these factors to inhibit proliferation of TF-1 cells induced by GM-CSF. The bioassays can be used also with Epo and TF-1 cells, or Epo and Epo-transfected UT-7 cells. |
Synonyms | IFN Omega; IFN-ω |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
SKU | GSCRPT-Z02909-20 |
---|---|
Supplier Part Number | Z02909-20 |
UM | EA |
UNSPSC | 41105300 |
Manufacturer | GenScript USA Inc |
ProductLine | GSCRPT |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 7 Business Days |
Hazardous | N |