Roche Diagnostics NEXES REAGENT, CELL MARQUE, FASCIN; ROCHGSK-05268117001

Roche Diagnostics Corporation NEXES REAGENT, CELL MARQUE, FASCIN; Anti-Fascin is a very sensitive marker for Reed-Sternberg cells and variants in nodular sclerosis, mixed cellularity, and lymphocyte depletion Hodgkins disease. It is uniformly negative in lymphoid cells, plasma cells and myeloid cells. Anti-Fascin is positive in dendritic cells. This marker may be helpful in distinguishing between Hodgkins disease and non-Hodgkins lymphoma in difficult cases. Also, the lack of expression of fascin in the neoplastic follicles in follicular lymphoma can be helpful in distinguishing these lymphomas from reactive follicular hyperplasia in which the number of follicular dendritic cells is normal or increased. Anti-Fascin has been suggested as a prognostic marker in neuroendocrine neoplasms of the lung, as well as ovarian cancer. 50 Tests - ROCHGSK (Additional S&H or Hazmat Fees May Apply)