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Roche Diagnostics Corporation Nexes, Reagent, Cell Marque, Act H
Roche Diagnostics Corporation Nexes, Reagent, Cell Marque, Act H - ROCHMSD (Additional S&H or Hazmat Fees May Apply)
List Price
$504.13
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$504.13
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NETA PART: | ROCHMSD-05268176001 |
MFG.PART: | 05268176001 |
UNSPSC: | 41116123 |
Manufacturer: | Roche Life Science |
Roche Diagnostics Corporation nexes, reagent, cell marque, act h; acth is synthesized from pre-pro-opiomelanocortin (pre-pomc). the removal of the single peptide during translation produces the 267 amino acid polypeptide pomc, which undergoes a series of post-translational modifications such as phosphorylation and glycosylation before it is proteolytically cleaved by endopeptidases to yield various polypeptide fragments with varying physiological activity. these fragments include acth, ±-lipotropin, -lipotropin, melanocyte stimulating hormone (msh), and ±-endorphin. pomc, acth, and ±-lipotropin are secreted from corticotropes in the anterior lobe (or adenohypophysis) of the pituitary gland in response to the hormone corticotropin-releasing hormone (crh) released by the hypothalamus. acth is also produced by cells of immune system (t-cells, b-cells, and macrophages) in response to stimuli associated with stress. anti-acth is a useful marker in classification of pituitary tumors and the study of pituitary disease. it reacts with acth-producing cells (corticotrophs). it also may react with other tumors (e.g. some small cell carcinomas of the lung) causing paraneoplastic syndromes by secreting acth. - ROCHMSD (Additional S&H or Hazmat Fees May Apply)
SKU | ROCHMSD-05268176001 |
---|---|
Supplier Part Number | 05268176001 |
UM | UN |
UNSPSC | 41116123 |
Manufacturer | Roche Life Science |
Refrigerated-Frozen | Refrig +2 to +8C |
ProductLine | ROCHMSD |
Qty | 1 |
MinOrderQty | 1 |
Depth | 2.6 |
Height | 6 in |
Weight | 7.00 |
Lead Time | 5 Business Days |
Hazardous | N |