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Cell Signaling Catalase (D5n7v) Rabbit mAb
Cell Signaling Catalase (D5n7v) Rabbit mAb - CSIG (Additional S&H or Hazmat Fees May Apply)
List Price
$327.00
Your Price
$327.00
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| NETA PART: | CSIG-14097S |
| MFG.PART: | 14097S |
| UNSPSC: | 12352300 |
| Manufacturer: | Cell Signaling |
| Size | 100 µl |
| Reactivity | H M R Mk |
| Sensitivity | Endogenous |
| Molecular Weight (kDa) | 60 |
| Source/Isotype | Rabbit IgG |
| Application/Dilution | {Western Blotting: 1:1000} |
| Storage | Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody. |
| Specificity/Sensitivity | Catalase (D5N7V) Rabbit mAb recognizes endogenous levels of total catalase protein. This antibody may also cross-react with an unidentified protein of approximately 35 kDa. |
| Species Reactivity | Human, Mouse, Rat, Monkey |
| Source/Purification | Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Asp128 of human catalase protein. |
| Background | Catalase catalyzes the conversion of hydrogen peroxide to water and oxygen (1). Research studies show that overexpression of this antioxidant enzyme increases the ability of pancreatic β-cells to scavenge reactive oxygen species (ROS), thereby protecting pancreatic β-cells from oxidative stress (2). The pancreatic β-cells overexpressing this enzyme are also protected from hydrogen peroxide-mediated lipotoxicity, providing further evidence for the importance of catalase in the pathogenesis of diabetes (3). |
| SKU | CSIG-14097S |
|---|---|
| Supplier Part Number | 14097S |
| UM | UNIT |
| UNSPSC | 12352300 |
| Manufacturer | Cell Signaling |
| MSDS URL | https://www.cellsignal.com/contents/technical/safety-data-sheet-(sds)/resources-safety-data-sheets |
| Temperature | -20C |
| ProductLine | CSIG |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 5 Business Days |
| Hazardous | N |