DWK Kimble Chase Dounce Tissue Grinder Kit, 2mL

DWK Kimble Chase KONTES Dounce Tissue Grinder Kit, 2 mL Volume, Borosilicate Glass, 60 mm L Tube, 0.0005 to 0.0025 in Pestle B Small Clearance, 0.003 to 0.005 in Pestle A Large Clearance 2mL. Tissue grinders produce homogenates by a combination of shearing and compression actions. The tissue sample is progressively ground (sheared) into smaller pieces at the rounded end of the pestle as the spinning pestle is lowered into the tube. As the pestle is forced lower into the tube, the sample is displaced and forced between the straight outside wall of the pestle and the inside wall of the tube, compressing the tissue cells until they rupture. When the tube is pulled away from the pestle, a slight vacuum is created that pulls the sample back past the compression area, resulting in an additional homogenization stroke. The degree of homogenization is controlled by the clearance between the pestles and tubes cylindrical section, the rotational speed of the pestle and the number of compression strokes made - KMBL