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Millipore Anti-Rig-I, C-Terminus Antibody Is An Antibody Against Rig-I, C-Terminus For Use In Western Blotting. - Mill (Additional S&H or Hazmat Fees May Apply)
Retinoic acid-inducible gene 1 (RIG-1, DDX58) is a cytoplasmic protein belonging to the family of RIG-1-like receptor (RLR) family. It is a multidomain protein containing an N-terminal caspase recruitment domain (CARD); a DExD/H box helicase domain; and a C-terminal repression domain. RIG-1 has a well-documented role in innate immunity, as a virus-sensing protein that detects viral RNA molecules and induces the production of IFN-β through activation of the inflammasome complex.
Product Information
Format
Affinity Purified
Control
Untreated A549 cell lysate and A549 cell lysate infected with 40 HAU/mL of SeV for12 hours.
Presentation
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality Level
MQ100
Applications
Application
Anti-RIG-I, C-terminus Antibody is an antibody against RIG-I, C-terminus for use in Western Blotting.
Key Applications
Western Blotting
Biological Information
Immunogen
KLH-conjugated linear peptide corresponding to the C-terminus of human RIG-I.
Epitope
C-terminus
Concentration
Please refer to the Certificate of Analysis for the lot-specific concentration.
Host
Rabbit
Specificity
This antibody recognizes the C-terminus of RIG-I.
Species Reactivity
Human
Antibody Type
Polyclonal Antibody
Entrez Gene Number
NP_055129
Gene Symbol
DDX58
Purification Method
Affinity Purfied
UniProt Number
O95786
Molecular Weight
~102 kDa observed
Product Usage Statements
Quality Assurance
Evaluated by Western Blot in untreated A549 cell lysate and A549 cell lysate infected with 40 HAU/mL of SeV for 12 hours.
Western Blot Analysis: 1 µg/mL of this antibody detected RIG-I in 10 µg of untreated A549 cell lysate and A549 cell lysate infected with 40 HAU/mL of SeV for12 hours..
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
