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Millipore Active, N-Terminal 6his-Tagged, Recombinant, Human Ark5, Amino Acids 2-End, For Use In Kinase Assays. - Mill (Additional S&H or Hazmat Fees May Apply)
N-terminal 6His-tagged, recombinant, human ARK5, amino acids 2-end
Product Information
Quality Level
MQ100
Applications
Application
Active, N-terminal 6His-tagged, recombinant, human ARK5, amino acids 2-end, for use in Kinase Assays.
Key Applications
Kinase Assay
Biological Information
Source
Expressed by baculovirus in Sf21 cells
Specific Activity
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Entrez Gene Number
NM_014840.2
Gene Symbol
NUAK1
KIAA0537
ARK5
NuaK1
Protein Target
NuaK1 (ARK5)
Purification Method
Ni2+/NTA-agarose
Target Sub-Family
CAMK
UniProt Number
O60285
UniProt Summary
FUNCTION: SwissProt: O60285 # Involved in tolerance to glucose starvation. Phosphorylates ATM. Suppresses Fas-induced apoptosis by phosphorylation of CASP6, thus suppressing the activation of the caspase and the subsequent cleavage of CFLAR. COFACTOR: Magnesium. SIZE: 661 amino acids; 74305 Da TISSUE SPECIFICITY: Expressed at high levels in heart and brain, and at lower levels in skeletal muscle, kidney, ovary, placenta, lung and liver. SIMILARITY: SwissProt: O60285 ## Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily. & Contains 1 protein kinase domain.
Molecular Weight
78kDa
Product Usage Statements
Quality Assurance
Routinely evaluated by phosphorylation of CHKtide
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions
Stable for 6 months at -70°C from date of shipment