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N-terminal 6His-tagged, recombinant, full length PKG1α.
Product Information
Quality Level
MQ100
Applications
Application
Active, N-terminal 6His-tagged, recombinant, full length PKG1α. For use in Kinase Assays.
Key Applications
Kinase Assay
Biological Information
Source
PKG1α, expressed by baculovirus in Sf21 cells.
Specific Activity
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Entrez Gene Number
NM_001098512.1
NM_006258.2
Gene Symbol
PRKG1
cGKI-beta
FLJ36117
PGK
PRKGR1A
cGKI-alpha
cGKI
MGC71944
OTTHUMP00000061216
CGKI
PRKG1B
cGKI-BETA
PRKGR1B
DKFZp686K042
Protein Target
PKG1α
Purification Method
Ni2+/NTA-agarose
Target Sub-Family
AGC
UniProt Number
P14619
UniProt Summary
SIZE: 686 amino acids; 77804 Da SUBUNIT: Antiparallel homodimer. Part of cGMP kinase signaling complex at least composed of ACTA2/alpha-actin, CNN1/calponin H1, PLN/phospholamban, PRKG1 and ITPR1 (By similarity). Interacts with MRVI1. DOMAIN: SwissProt: P14619 SIMILARITY: SwissProt: P14619 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily. & Contains 1 AGC-kinase C-terminal domain. & Contains 2 cyclic nucleotide-binding domains. & Contains 1 protein kinase domain. | Q13976 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily. & Contains 1 AGC-kinase C-terminal domain. & Contains 2 cyclic nucleotide-binding domains. & Contains 1 protein kinase domain. MISCELLANEOUS: Exhibit a substrate specificity similar but not identical to that of CAK.
Molecular Weight
80kDa
Product Usage Statements
Quality Assurance
routinely evaluated by phosphorylation of PAKtide (RRRLSFAEPG).
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
