We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Share this :
Print
Miltenyi Biotec Cd184 (Cxcr4) Antibody, Anti-Human, Pe-Vio 770,
Miltenyi Biotec Cd184 (Cxcr4) Antibody, Anti-Human, Pe-Vio 770, Reafinity - MLTY (Additional S&H or Hazmat Fees May Apply)
List Price
$181.50
Your Price
$181.50
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | MLTY-130-120-797 |
MFG.PART: | 130-120-797 |
UNSPSC: | 12352203 |
Manufacturer: | Miltenyi Biotec |
Miltenyi Biotec Clone REA649 recognizes the human CD184 antigen, a multi-pass membrane protein, also known as C-X-C chemokine receptor type 4 (CXCR4), leukocyte-derived seven transmembrane domain receptor (LESTR), or fusin. CD184 is ubiquitously expressed on blood and tissue cells. It mediates chemotaxis in mature and progenitor blood cells and is important for B lymphopoiesis, myelopoiesis, and cardiogenesis. CD184 exclusively interacts with the endogenous ligand CXCL12. Binding of CXCL12 transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Although CXCL12 is the only known chemokine that binds CD184, recent studies suggest that extracellular ubiquitin also acts as an immune modulator through CD184-mediated signaling. CD184 is a coreceptor for HIV entry by promoting Env-mediated fusion of the virus. | Additional information: Clone REA649 displays negligible binding to Fc receptors. - MLTY (Additional S&H or Hazmat Fees May Apply)
SKU | MLTY-130-120-797 |
---|---|
Supplier Part Number | 130-120-797 |
UM | EA |
UNSPSC | 12352203 |
Manufacturer | Miltenyi Biotec |
MSDS URL | https://www.miltenyibiotec.com/ds/130-120-797 |
ProductLine | MLTY |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 5 Business Days |
Hazardous | N |