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Miltenyi Biotec Cd94 Antibody, Anti-Human, Fitc, Reafinity
Miltenyi Biotec Cd94 Antibody, Anti-Human, Fitc, Reafinity - MLTY (Additional S&H or Hazmat Fees May Apply)
List Price
$104.50
Your Price
$104.50
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | MLTY-130-123-924 |
MFG.PART: | 130-123-924 |
UNSPSC: | 12352203 |
Manufacturer: | Miltenyi Biotec |
Miltenyi Biotec The clone REA113 recognizes CD94, an approximately 45 kDa, single-pass type II transmembrane protein, which belongs to the C-type lectin superfamily. CD94 associates covalently with NKG2 family members and forms disulfide bonded heterodimers. CD94-NKG2 receptors bind HLA-E, the non-classical MHC class Ib molecule. Depending on the associated NKG2 member, CD94-NKG2 heterodimer transmits either activating or inhibitory signal. For, e.g, via immunoreceptor tyrosine based-inhibitory motifs (ITIMs) containing NKG2A, CD94-NKG2A heterodimers inhibit NK cell cytotoxicity. Besides NK cells, expression of CD94-NKG2 heterodimers is also shown on NK-T cells and a small percentage of CD8 cells in mice, where the crosslinking of CD94-NKG2 was shown to reduce the level of spontaneous apoptosis. | Additional information: Clone REA113 displays negligible binding to Fc receptors. | - MLTY (Additional S&H or Hazmat Fees May Apply)
SKU | MLTY-130-123-924 |
---|---|
Supplier Part Number | 130-123-924 |
UM | EA |
UNSPSC | 12352203 |
Manufacturer | Miltenyi Biotec |
MSDS URL | https://www.miltenyibiotec.com/ds/130-123-924 |
ProductLine | MLTY |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 5 Business Days |
Hazardous | N |