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Miltenyi Biotec Cd366 (Tim-3) Antibody, Anti-Human, Apc, Realease
Miltenyi Biotec Cd366 (Tim-3) Antibody, Anti-Human, Apc, Realease - MLTY (Additional S&H or Hazmat Fees May Apply)
List Price
$429.00
Your Price
$429.00
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NETA PART: | MLTY-130-125-770 |
MFG.PART: | 130-125-770 |
UNSPSC: | 12352203 |
Manufacturer: | Miltenyi Biotec |
Miltenyi Biotec Clone REAL226 is an antibody fragment derived from the full CD366 (TIM-3) antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAlease Complex to bind markers with high avidity. | Clone REAL226 recognizes the human CD366 antigen, a single-pass type I membrane protein which is also known as T cell immunoglobulin and mucin domain containing protein-3 (TIM-3) or Hepatitis A virus cellular receptor 2 (HAVcr-2). CD366 is expressed on activated T cells, especially Tʜ1 cells, monocytes, macrophages, and dendritic cells. It is an activation-induced inhibitory molecule involved in tolerance and shown to induce T cell exhaustion in chronic viral infection and cancers. CD366 has been proposed to inhibit Tʜ1-mediated immune responses and regulates Tʜ1 and Tʜ17 cytokine secretion. The interaction of CD366 and its ligand galectin-9 induces apoptosis of Tʜ1 cells. | The REAlease Kits consist of the respective fluorochrome-conjugated REAlease Complexes and the REAlease Support Kit for removal of the REAlease Complexes and optional relabeling with different fluorochrome-conjugated REAlease Complexes. - MLTY (Additional S&H or Hazmat Fees May Apply)
SKU | MLTY-130-125-770 |
---|---|
Supplier Part Number | 130-125-770 |
UM | EA |
UNSPSC | 12352203 |
Manufacturer | Miltenyi Biotec |
MSDS URL | https://www.miltenyibiotec.com/ds/130-125-770 |
ProductLine | MLTY |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 5 Business Days |
Hazardous | N |