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Miltenyi Biotec Cd6 Antibody, Anti-Mouse, Fitc, Reafinity
Miltenyi Biotec Cd6 Antibody, Anti-Mouse, Fitc, Reafinity - MLTY (Additional S&H or Hazmat Fees May Apply)
List Price
$60.50
Your Price
$60.50
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | MLTY-130-126-502 |
MFG.PART: | 130-126-502 |
UNSPSC: | 12352203 |
Manufacturer: | Miltenyi Biotec |
Miltenyi Biotec Clone REA311 recognizes the murine CD6 antigen, a Single-pass type I membrane protein which is expressed on most CD4+CD8+ double-positive, CD4+ or CD8+ single-positive thymocytes, and at highest levels on mature CD3+ thymocytes. In marked contrast to human CD6, mouse CD6 has a long cytoplasmic tail that is not closely related to other proteins. CD6 functions as an adhesion molecule as well as costimulatory molecule for TCR-mediated T cell activation. In thymocytes that express heterogeneous TCR, CD6 increases occur as double-positive thymocytes are selected to a single-positive stage. In contrast, in thymocytes from TCR transgenic mice, CD6 is barely increased following selection, suggesting that as functional avidity increases, requirements for CD6-dependent co-stimulation decrease. During thymic development CD6-dependent signals may contribute both to thymocyte survival, and to the overall functional avidity of selection. | Additional information: Clone REA311 displays negligible binding to Fc receptors. | - MLTY (Additional S&H or Hazmat Fees May Apply)
SKU | MLTY-130-126-502 |
---|---|
Supplier Part Number | 130-126-502 |
UM | EA |
UNSPSC | 12352203 |
Manufacturer | Miltenyi Biotec |
MSDS URL | https://www.miltenyibiotec.com/ds/130-126-502 |
ProductLine | MLTY |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 5 Business Days |
Hazardous | N |