We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Share this :
Print
Genscript DNAM-1/CD226, His, Human
Genscript DNAM-1/CD226, His, Human - GSCRPT (Additional S&H or Hazmat Fees May Apply)
List Price
$200.00
Your Price
$200.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | GSCRPT-Z03455-100 |
MFG.PART: | Z03455-100 |
UNSPSC: | 12352202 |
Manufacturer: | GenScript USA Inc |
Product Introduction
Species | Human | ||||
Protein Construction |
| ||||
Purity | > 90% as analyzed by SDS-PAGE | ||||
Endotoxin Level | < 1 EU/μg of protein by gel clotting method | ||||
Biological Activity | DNAM-1/CD226, His, Human can bind with CHO-K1/aAPC/CD155 Clone by FACS analysis. | ||||
Expression System | HEK 293 | ||||
Apparent Molecular Weight | ~39.3 kDa, on SDS-PAGE under reducing conditions. | ||||
Formulation | Lyophilized from a 0.2 μm filtered solution in PBS. | ||||
Reconstitution | It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O or PBS up to 100 μg/ml. | ||||
Storage & Stability | Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles. |
Background
Target Background | CD226 (Cluster of Differentiation 226), also known as PTA1 (outdated term, platelet and T cell activation antigen 1)[5] or DNAM-1 (DNAX Accessory Molecule-1), is a ~65 kDa glycoprotein expressed on the surface of natural killer cells, platelets, monocytes and a subset of T cells. It is a member of the immunoglobulin superfamily. This protein is involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell. It is the cell surface receptor for NECTIN2 and its main ligands are CD112 and CD155. It stimulates T-cell proliferation and cytokine production, including that of IL-2, IL-5, IL-10, IL-13, and IFNγ upon ligand binding. |
Synonyms | DNAM-1; DNAM1; PTA1; TLiSA1; CD226 molecule |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
SKU | GSCRPT-Z03455-100 |
---|---|
Supplier Part Number | Z03455-100 |
UM | EA |
UNSPSC | 12352202 |
Manufacturer | GenScript USA Inc |
ProductLine | GSCRPT |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 7 Business Days |
Hazardous | N |