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Genscript CD73, His, Human
Genscript CD73, His, Human - GSCRPT (Additional S&H or Hazmat Fees May Apply)
List Price
$2,400.00
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$2,400.00
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| NETA PART: | GSCRPT-Z03628-1 |
| MFG.PART: | Z03628-1 |
| UNSPSC: | 12352202 |
| Manufacturer: | GenScript USA Inc |
Product Introduction
| Species | Human | ||||
| Protein Construction |
| ||||
| Purity | > 95% as analyzed by SDS-PAGE > 95% as analyzed by HPLC | ||||
| Endotoxin Level | ≤ 1 EU/μg of protein by LAL method | ||||
| Biological Activity | Immobilized Human CD73, His at 0.5 μg/ml (100 μl/Well). Dose response curve for Anti-CD73 Ab with the EC50 of 19.3 ng/ml determined by ELISA. | ||||
| Expression System | Expi293 | ||||
| Apparent Molecular Weight | ~58.8 kDa, on SDS-PAGE under reducing conditions. | ||||
| Formulation | Supplied as a 0.22 μm filtered solution in 20 mM Tris, 120 mM NaCl, 4 mM CaCl2, 20% glycerol, pH 7.5. | ||||
| Concentration | Please refer to the COA for the specific lot. | ||||
| Storage & Stability | Upon receiving, this product remains stable for up to 6 months at -70°C or -20°C. Avoid repeated freeze-thaw cycles. |
Background
| Target Background | CD73, also known as ecto-5-nucleotidase, is an enzyme that in humans is encoded by the NT5E gene.CD73 commonly serves to convert AMP to adenosine.The enzyme consists of a dimer of 2 identical 70-kD subunits bound by a glycosyl phosphatidyl inositol linkage to the external face of the plasma membrane. The enzyme is used as a marker of lymphocyte differentiation. A deficiency of CD73 occurs in a variety of immunodeficiency diseases. |
| Synonyms | CD73 antigen; CD73; NT5E; NTE; 5 nucleotidase (CD73); 5-NT; 5-NT; 5-Nucleotidase; 5-nucleotidase, ecto (CD73); E5NT; EC 3.1.3.5; ecto-5-nucleotidase; eN; eNT; NT; NT55-nucleotidase; Purine 5-Prime-Nucleotidase |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
| SKU | GSCRPT-Z03628-1 |
|---|---|
| Supplier Part Number | Z03628-1 |
| UM | EA |
| UNSPSC | 12352202 |
| Manufacturer | GenScript USA Inc |
| ProductLine | GSCRPT |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 7 Business Days |
| Hazardous | N |