We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Share this :
Print
Cell Signaling Ccl5/Rantes (E9s2k) Rabbit mAb
Cell Signaling Ccl5/Rantes (E9s2k) Rabbit mAb - CSIG (Additional S&H or Hazmat Fees May Apply)
List Price
$343.00
Your Price
$343.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CSIG-36467S |
MFG.PART: | 36467S |
UNSPSC: | 12352203 |
Manufacturer: | Cell Signaling |
Size | 100 µl |
Reactivity | H M |
Sensitivity | Endogenous |
Molecular Weight (kDa) | 10 |
Source/Isotype | Rabbit IgG |
Application/Dilution | {Western Blotting: 1:1000, Immunohistochemistry (Paraffin): 1:150 - 1:600} |
Storage | Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody. For a carrier-free (BSA and azide free) version of this product see product #57219. |
Specificity/Sensitivity | CCL5/RANTES (E9S2K) Rabbit mAb recognizes endogenous levels of total CCL5/RANTES protein. This antibody recognizes human CCL5/RANTES protein and is also reactive with mouse CCL5/RANTES; however, this antibody is not suggested for immunohistochemical analysis of mouse tissues. Non-specific staining was observed in human pancreatic islets by immunohistochemistry. |
Species Reactivity | Human, Mouse |
Source/Purification | Monoclonal antibody is produced by immunizing animals with human CCL5/RANTES recombinant protein. |
Background | RANTES/CCL5 (regulated upon activation, T cell expressed and secreted) is a member of the "C-C" or β family of chemokines that induce inflammation and are associated with a number of inflammatory disorders (1,2). RANTES is produced and secreted mainly by CD8+ T cells, macrophages, and platelets, as well as epithelial cells, fibroblasts, and some solid tumors (2-7). RANTES acts as a chemoattractant and has other regulatory functions on a number of cell types, including monocytes, memory T cells, NK cells, eosinophils, basophils, dendritic cells, and mast cells (3, 7-9). Signaling by RANTES is mediated by several G protein-coupled receptors (GPCRs), including CCR1, CCR3, CCR4, and CCR5. |
SKU | CSIG-36467S |
---|---|
Supplier Part Number | 36467S |
UM | EA |
UNSPSC | 12352203 |
Manufacturer | Cell Signaling |
CountryOfOrigin | US |
ProductLine | CSIG |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 5 Business Days |
Hazardous | N |