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Cell Signaling Keratin 14 (Ll002) Mouse mAb
Cell Signaling Keratin 14 (Ll002) Mouse mAb - CSIG (Additional S&H or Hazmat Fees May Apply)
List Price
$348.00
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$348.00
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NETA PART: | CSIG-48020S |
MFG.PART: | 48020S |
UNSPSC: | 12352203 |
Manufacturer: | Cell Signaling |
Size | 100 µl |
Reactivity | H |
Sensitivity | Endogenous |
Source/Isotype | Mouse IgG3 |
Application/Dilution | {IHC Leica Bond: 1:100 - 1:400, Immunohistochemistry (Paraffin): 1:50 - 1:200} |
Storage | Supplied in a PBS-based buffer with ~1% BSA and less than 0.1% sodium azide. Stable for 6 months when stored at 4°C. Do not aliquot the antibody. |
Specificity/Sensitivity | Keratin 14 (LL002) Mouse mAb recognizes endogenous levels of keratin 14 protein. |
Species Reactivity | Human |
Source/Purification | Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human keratin 14 protein. |
Background | Keratins (cytokeratins) are intermediate filament proteins that are mainly expressed in epithelial cells. Keratin heterodimers composed of an acidic keratin (or type I keratin, keratins 9 to 23) and a basic keratin (or type II keratin, keratins 1 to 8) assemble to form filaments (1,2). Keratin isoforms demonstrate tissue- and differentiation-specific profiles that make them useful as research biomarkers (1). Research studies have shown that mutations in keratin genes are associated with skin disorders, liver and pancreatic diseases, and inflammatory intestinal diseases (3-6). |
SKU | CSIG-48020S |
---|---|
Supplier Part Number | 48020S |
UM | EA |
UNSPSC | 12352203 |
Manufacturer | Cell Signaling |
MSDS URL | https://www.cellsignal.com/contents/technical/safety-data-sheet-(sds)/resources-safety-data-sheets |
Temperature | +4C |
CountryOfOrigin | US |
ProductLine | CSIG |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 5 Business Days |
Hazardous | N |