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Miltenyi Biotec Anti-Il-12 (P40/P70)-Pe, H, C8.6, 30 T
Miltenyi Biotec Identification And Enumeration Of Il-12 (P40/P70)+ Cells By Flow Cytometry - MLTY (Additional S&H or Hazmat Fees May Apply)
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$165.00
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$165.00
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NETA PART: | MLTY-130-123-312 |
MFG.PART: | 130-123-312 |
UNSPSC: | 12352203 |
Manufacturer: | Miltenyi Biotec |
Miltenyi Biotec Interleukin 12 (IL-12) is a 70–75 kDa heterodimeric cytokine composed of a 40 kDa heavy chain and a 35 kDa light chain. It is produced mainly by monocytes and macrophages as well as dendritic cells, primarily in response to stimulation with bacterial or viral antigens. IL-12 has also been described to be produced by non-hematopoietic cells such as keratinocytes and epidermoid carcinomas. IL-12 displays various effects on both T and NK cells, playing an essential role in the interaction between innate and adaptive immunity, for example, it induces the production of IFN-γ alone or in synergy with IL-2, is a co-stimulator of both NK and T cell proliferation, and enhances cytolytic activity of both cell types. Moreover, IL-12 promotes the development of T helper 1 (Tʜ1)-specific immune responses by promoting the differentiation of CD4+ cells towards a Tʜ1 phenotype while inhibiting the production of Tʜ2 cells. | Clone C8.6 reacts with both, the p40 chain and the p70 heterodimer of human, rhesus monkey, and cynomolgus monkey IL-12. - MLTY (Additional S&H or Hazmat Fees May Apply)
SKU | MLTY-130-123-312 |
---|---|
Supplier Part Number | 130-123-312 |
UM | EA |
UNSPSC | 12352203 |
Manufacturer | Miltenyi Biotec |
MSDS URL | https://www.miltenyibiotec.com/ds/130-123-312 |
ProductLine | MLTY |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 5 Business Days |
Hazardous | N |