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Miltenyi Biotec Cd324 (E-Cadherin) Antibody, Anti-Human, Pe, Reafinity™
Miltenyi Biotec Recombinant Antibody For The Detection Of Cd324 (E-Cadherin)+ Cells - MLTY (Additional S&H or Hazmat Fees May Apply)
List Price
$357.50
Your Price
$357.50
HOW MUCH YOU SAVE:
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NETA PART: | MLTY-130-127-980 |
MFG.PART: | 130-127-980 |
UNSPSC: | 12352203 |
Manufacturer: | Miltenyi Biotec |
Miltenyi Biotec Clone REA1319 recognizes human CD324, also known as E-cadherin or cadherin-1, which is a calcium-dependent cell adhesion protein found in adherence junctions of epithelial cells, e.g., in colon, uterus, liver, keratinocytes, etc. E-cadherin also serves as a ligand for integrin α-E/β-7. The epitope is expressed by a variety of carcinoma-derived cell lines such as MCF-7, HT-29, T-47D, NTERA-2, and 2102Ep. Loss of E-cadherin is thought to enable metastasis by disrupting intercellular contacts – an early step in metastatic dissemination. Furthermore, E-cadherin is a marker of undifferentiated embryonic stem (ES) cells and induced pluripotent stem (iPS) cells. For these cells, E-cadherin plays a major role in conveying cell survival signals. Mutations in CD324, which lead to loss of function or expression has been implicated in cancer progression and metastasis. Additional information: Clone REA1319 displays negligible binding to Fc receptors. | - MLTY (Additional S&H or Hazmat Fees May Apply)
SKU | MLTY-130-127-980 |
---|---|
Supplier Part Number | 130-127-980 |
UM | EA |
UNSPSC | 12352203 |
Manufacturer | Miltenyi Biotec |
MSDS URL | https://www.miltenyibiotec.com/ds/130-127-980 |
ProductLine | MLTY |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 5 Business Days |
Hazardous | N |