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Cell Signaling Cd11c (N418) Hamster mAb (Fitc Conjugate)
Cell Signaling Cd11c (N418) Hamster mAb (Fitc Conjugate) - CSIG (Additional S&H or Hazmat Fees May Apply)
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$103.00
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$103.00
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| NETA PART: | CSIG-51419S |
| MFG.PART: | 51419S |
| UNSPSC: | 12352203 |
| Manufacturer: | Cell Signaling |
| Size | 100 µg |
| Reactivity | M |
| Sensitivity | Endogenous |
| Source/Isotype | Hamster (Armenian) IgG |
| Application/Dilution | {Flow Cytometry (Live): 1:200} |
| Storage | Supplied in 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2. This product is stable for 12 months when stored at 4ºC. Do not aliquot the antibody. Protect from light. Do not freeze. |
| Specificity/Sensitivity | CD11c (N418) Hamster mAb (FITC Conjugate) recognizes endogenous levels of total CD11c protein. This antibody detects an epitope within the extracellular domain. |
| Species Reactivity | Mouse |
| Source/Purification | This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation. |
| Background | CD11c (integrin αX, ITGAX) is a transmembrane glycoprotein that forms an α/β heterodimer with CD18 (integrin β2), which interacts with a variety of extracellular matrix molecules and cell surface proteins (1). CD11c is primarily used as a dendritic cell marker. Dendritic cells can be classified into two major types: CD11c+ conventional dendritic cells that specialize in antigen presentation, and CD11c- plasmacytoid dendritic cells that specialize in type I interferon production (2, 3). CD11c expression has also been observed on activated NK cells, subsets of B cells, monocytes, granulocytes, and some B cell malignancies including hairy cell leukemia (4-7).The N418 antibody is widely used as a marker for CD11c expression on the cell types mentioned above (8,9). |
| SKU | CSIG-51419S |
|---|---|
| Supplier Part Number | 51419S |
| UM | EA |
| UNSPSC | 12352203 |
| Manufacturer | Cell Signaling |
| CountryOfOrigin | US |
| ProductLine | CSIG |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 5 Business Days |
| Hazardous | N |