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Cell Signaling Capza1 (E3u1g) Rabbit mAb
Cell Signaling Capza1 (E3u1g) Rabbit mAb - CSIG (Additional S&H or Hazmat Fees May Apply)
List Price
$327.00
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$327.00
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NETA PART: | CSIG-62114S |
MFG.PART: | 62114S |
UNSPSC: | 12352203 |
Manufacturer: | Cell Signaling |
Size | 100 µl |
Reactivity | H M R |
Sensitivity | Endogenous |
Molecular Weight (kDa) | 33 |
Source/Isotype | Rabbit IgG |
Application/Dilution | {Western Blotting: 1:1000} |
Storage | Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody. |
Specificity/Sensitivity | CAPZA1 (E3U1G) Rabbit mAb recognizes endogenous levels of total CAPZA1 protein. This antibody does not cross-react with CAPZA2 protein. Based on the sequence of the peptide antigen, this antibody is not expected to cross-react with CAPZA3 protein. |
Species Reactivity | Human, Mouse, Rat |
Source/Purification | Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Arg86 of human CAPZA1 protein. |
Background | The F-actin-capping protein, a ubiquitously expressed heterodimer composed of structurally similar α and β subunits, regulates cytoskeletal organization and function by binding to the actin filament barbed ends and maintaining the cellular pool of monomeric actin (1).F-actin-capping protein subunit α-1 (CAPZA1) overexpression is linked to more favorable prognosis in gastric cancer (2). In hepatocellular carcinoma, CAPZA1 inhibits epithelial-mesenchymal transition (EMT), migration, and invasion (3,4). |
SKU | CSIG-62114S |
---|---|
Supplier Part Number | 62114S |
UM | EA |
UNSPSC | 12352203 |
Manufacturer | Cell Signaling |
ProductLine | CSIG |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 5 Business Days |
Hazardous | N |