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Cell Signaling Cd11c (3.9) Mouse mAb (Violetfluor 450 Conjugate)
Cell Signaling Cd11c (3.9) Mouse mAb (Violetfluor 450 Conjugate) - CSIG (Additional S&H or Hazmat Fees May Apply)
List Price
$302.00
Your Price
$302.00
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NETA PART: | CSIG-97473S |
MFG.PART: | 97473S |
UNSPSC: | 12352203 |
Manufacturer: | Cell Signaling |
Size | 500 µl (100 tests) |
Reactivity | H |
Sensitivity | Endogenous |
Source/Isotype | Mouse IgG1 |
Application/Dilution | {Flow Cytometry (Fixed/Permeabilized): 1:20, Flow Cytometry (Live): 1:20} |
Storage | Supplied in 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2. This product is stable for 12 months when stored at 4ºC. Do not aliquot the antibody. Protect from light. Do not freeze. |
Specificity/Sensitivity | CD11c (3.9) Mouse mAb (violetFluor™ 450 Conjugate) recognizes endogenous levels of total CD11c protein. This antibody detects an epitope within the extracellular domain. |
Species Reactivity | Human |
Source/Purification | This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation. |
Background | CD11c (integrin αX, ITGAX) is a transmembrane glycoprotein that forms an α/β heterodimer with CD18 (integrin β2), which interacts with a variety of extracellular matrix molecules and cell surface proteins (1). CD11c is primarily used as a dendritic cell marker. Dendritic cells can be classified into two major types: CD11c+ conventional dendritic cells that specialize in antigen presentation, and CD11c- plasmacytoid dendritic cells that specialize in type I interferon production (2, 3). CD11c expression has also been observed on activated NK cells, subsets of B cells, monocytes, granulocytes, and some B cell malignancies including hairy cell leukemia (4-7).The 3.9 antibody is widely used as a marker for CD11c expression on the above mentioned cell types. |
SKU | CSIG-97473S |
---|---|
Supplier Part Number | 97473S |
UM | EA |
UNSPSC | 12352203 |
Manufacturer | Cell Signaling |
MSDS URL | https://www.cellsignal.com/contents/technical/safety-data-sheet-(sds)/resources-safety-data-sheets |
Temperature | +4C |
ProductLine | CSIG |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 5 Business Days |
Hazardous | N |