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Cell Signaling Coronin 1a (D6k5b) Xp Rabbit mAb (Pe Conjugate)
Cell Signaling Coronin 1a (D6k5b) Xp Rabbit mAb (Pe Conjugate) - CSIG (Additional S&H or Hazmat Fees May Apply)
List Price
$435.00
Your Price
$435.00
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NETA PART: | CSIG-98455S |
MFG.PART: | 98455S |
UNSPSC: | 12352203 |
Manufacturer: | Cell Signaling |
Size | 100 µl (50 tests) |
Reactivity | H M |
Sensitivity | Endogenous |
Source/Isotype | Rabbit IgG |
Application/Dilution | {Flow Cytometry (Fixed/Permeabilized): 1:50} |
Storage | Supplied in PBS (pH 7.2), less than 0.1% sodium azide and 2 mg/ml BSA. Store at 4°C. Do not aliquot the antibody. Protect from light. Do not freeze. |
Specificity/Sensitivity | Coronin 1A (D6K5B) XP® Rabbit mAb (PE Conjugate) recognizes endogenous levels of total coronin 1A protein. Based on the sequence of the immunogenic peptide, this antibody is not expected to cross-react with other coronin protein family members. |
Species Reactivity | Human, Mouse |
Source/Purification | Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Val200 of human coronin 1A protein. |
Background | The coronin family of actin-binding proteins regulates a variety of cellular functions, including migration, phagocytosis, and cytokinesis. Coronin 1A is highly expressed in lymphocytes, and is required for appropriate immune regulation in mice and humans. Researchers are investigating coronin 1A as a potential therapeutic target for autoimmune diseases and lymphoid cancers (1,2). Coronin 1A affects bone resorption through its regulation of lysosome fusion and secretion of cathepsin K in osteoclasts (3). In the nervous system, coronin 1A has been shown to regulate GPCR signaling and neurite outgrowth (4,5). |
SKU | CSIG-98455S |
---|---|
Supplier Part Number | 98455S |
UM | EA |
UNSPSC | 12352203 |
Manufacturer | Cell Signaling |
MSDS URL | https://www.cellsignal.com/contents/technical/safety-data-sheet-(sds)/resources-safety-data-sheets |
Temperature | +4C |
ProductLine | CSIG |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 5 Business Days |