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Genscript IL-1B, Rat
Genscript IL-1B, Rat - GSCRPT (Additional S&H or Hazmat Fees May Apply)
List Price
$2,230.00
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$2,230.00
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NETA PART: | GSCRPT-Z03014-1 |
MFG.PART: | Z03014-1 |
UNSPSC: | 41106514 |
Manufacturer: | GenScript USA Inc |
Product Introduction
Species | Rat | |
Protein Construction |
| |
Purity | > 95% as analyzed by SDS-PAGE > 95% as analyzed by HPLC | |
Endotoxin Level | < 0.2 EU/μg of protein by gel clotting method | |
Biological Activity | ED50 < 10.0 pg/ml, measured by a cell proliferation assay using mouse D10S cells, corresponding to a specific activity of > 1.0 × 108 units/mg. | |
Expression System | E. coli | |
Apparent Molecular Weight | ~17.3 kDa, on SDS-PAGE under reducing conditions. | |
Formulation | Lyophilized after extensive dialysis against PBS. | |
Reconstitution | It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O up to 100 μg/ml. | |
Storage & Stability | Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles. |
Background
Target Background | Interleukin-1 Beta (IL-1 Beta) is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1 alpha and IL-1 beta bind to the same receptor and have similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1 beta is a secreted cytokine, IL-1 alpha is predominantly a cell-associated cytokine. |
Synonyms | IL1B; IL-1; IL1-BETA; IL1F2; interleukin 1 beta; IL1beta |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
SKU | GSCRPT-Z03014-1 |
---|---|
Supplier Part Number | Z03014-1 |
UM | EA |
UNSPSC | 41106514 |
Manufacturer | GenScript USA Inc |
ProductLine | GSCRPT |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 7 Business Days |