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Genscript IL-18, Rat
Genscript IL-18, Rat - GSCRPT (Additional S&H or Hazmat Fees May Apply)
List Price
$3,564.75
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$3,564.75
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NETA PART: | GSCRPT-Z03025-1 |
MFG.PART: | Z03025-1 |
UNSPSC: | 41106514 |
Manufacturer: | GenScript USA Inc |
Product Introduction
Species | Rat | |
Protein Construction | Expressed with an N-terminal Met.
| |
Purity | > 95% as analyzed by SDS-PAGE | |
Endotoxin Level | < 0.2 EU/μg of protein by gel clotting method | |
Biological Activity | ED50 < 2.0 μg/ml resulted in the secretion of 0.15 ng/ml h-IFN-gamma when tested using KG-1 cell line, corresponding to a specific activity of > 500.0 units/mg. | |
Expression System | E. coli | |
Apparent Molecular Weight | ~18.4 kDa, on SDS-PAGE under reducing conditions. | |
Formulation | Lyophilized after extensive dialysis against 50 mM Tris, 50 mM NaCl, pH 8.0. | |
Reconstitution | It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O up to 100 μg/ml. | |
Storage & Stability | Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles. |
Background
Target Background | Interleukin-18 (IL18, also known as interferon-gamma inducing factor or IGIF) is a cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other cells. Its biological activity is pleiotropic and it has been shown to induce interferon-gamma production in KG-1 cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production in B cells. |
Synonyms | IL18; IGIF; IL-18; IL-1g; IL1F4; interleukin 18 |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
SKU | GSCRPT-Z03025-1 |
---|---|
Supplier Part Number | Z03025-1 |
UM | EA |
UNSPSC | 41106514 |
Manufacturer | GenScript USA Inc |
ProductLine | GSCRPT |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 7 Business Days |