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Genscript IL-10, Rat
Genscript IL-10, Rat - GSCRPT (Additional S&H or Hazmat Fees May Apply)
List Price
$4,105.50
Your Price
$4,105.50
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| NETA PART: | GSCRPT-Z03578-1 |
| MFG.PART: | Z03578-1 |
| UNSPSC: | 41106514 |
| Manufacturer: | GenScript USA Inc |
Product Introduction
| Species | Rat | |
| Protein Construction |
| |
| Purity | > 97% as analyzed by SDS-PAGE > 97% as analyzed by HPLC | |
| Endotoxin Level | < 0.1 EU/µg of protein by LAL method | |
| Biological Activity | The ED50 as determined by a cell proliferation assay using murine MC/9-2 cells is less than 1.0 ng/ml, corresponding to a specific activity of 1.0 × 106 IU/mg. | |
| Expression System | E. coli | |
| Theoretical Molecular Weight | 18.6 kDa | |
| Formulation | Lyophilized from a 0.2 µm filtered solution in 20 mM Tris-HCl, pH 8.0, 100 mM NaCl. | |
| Reconstitution | It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/ml. | |
| Storage & Stability | Upon receiving, this product remains stable for up to 6 months at -20°C or -70°C. Upon reconstitution, the product should be stable for up to 1 week at 2-8°C or up to 3 months at -20°C. Avoid repeated freeze-thaw cycles. |
Background
| Target Background | Interleukin-10 (IL-10), also known as cytokine synthesis inhibitory factor (CSIF), is an anti-inflammatory cytokine produced by a variety of cell lines including T-cells, macrophages and mast cells. IL-10 is classified as a class-2 cytokine, a set of cytokines including IL-19, IL-20, IL-22, IL-24, and IL-26. IL-10 can inhibit the synthesis of pro-inflammatory cytokines such as IFN-gamma, IL-2, IL-3, TNF and GM-CSF. It also stimulates Th2 responses, but suppresses the antigen-presentation capacity of antigen presenting cells. |
| Synonyms | Cytokine synthesis inhibitory factor; CSIF; TGIF; IL10A |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
| SKU | GSCRPT-Z03578-1 |
|---|---|
| Supplier Part Number | Z03578-1 |
| UM | EA |
| UNSPSC | 41106514 |
| Manufacturer | GenScript USA Inc |
| ProductLine | GSCRPT |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 7 Business Days |