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Genscript OSM, Rat
Genscript OSM, Rat - GSCRPT (Additional S&H or Hazmat Fees May Apply)
List Price
$4,105.50
Your Price
$4,105.50
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| NETA PART: | GSCRPT-Z03588-1 |
| MFG.PART: | Z03588-1 |
| UNSPSC: | 41106514 |
| Manufacturer: | GenScript USA Inc |
Product Introduction
| Species | Rat | |
| Protein Construction |
| |
| Purity | > 96% as analyzed by SDS-PAGE > 96% as analyzed by HPLC | |
| Endotoxin Level | < 1 EU/μg of protein by LAL method | |
| Biological Activity | The ED50 as determined by a cell proliferation assay using murine NIH-3T3 cells is less than 2.0 ng/ml, corresponding to a specific activity of 5.0 × 105 IU/mg. | |
| Expression System | E. coli | |
| Theoretical Molecular Weight | 24.3 kDa | |
| Formulation | Lyophilized from a 0.2 μm filtered solution in 2 × PBS, 0.1 % Tween-80. | |
| Reconstitution | It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/ml. | |
| Storage & Stability | Upon receiving, this product remains stable for up to 6 months at -20°C or -70°C. Upon reconstitution, the product should be stable for up to 1 week at 2-8°C or up to 3 months at -20°C. Avoid repeated freeze-thaw cycles. |
Background
| Target Background | Oncostatin-M (OSM) is a multifunctional cytokine that belongs to the Interleukin-6 subfamily. Among the family members, OSM is most closely related to leukemia inhibitory factor (LIF) and it in fact utilizes the LIF receptor in addition to its specific receptor in the human. A biologically active OSM receptor has been previously described that consists of a heterodimer of leukemia inhibitory factor receptor (LIFR) and gp130. OSM is synthesized by stimulated T-cells and monocytes. Furthermore, the effects of OSM on endothelial cells suggest a pro-inflammatory role for OSM and endothelial cells possess a large number of OSM receptors. Recombinant murine OSM contains 215 amino acids and has a molecular mass of 22.4 kDa. It has approximately 48 % and 72 % amino acid sequence identity with human and murine OSM. |
| Synonyms | Oncostatin-M |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
| SKU | GSCRPT-Z03588-1 |
|---|---|
| Supplier Part Number | Z03588-1 |
| UM | EA |
| UNSPSC | 41106514 |
| Manufacturer | GenScript USA Inc |
| ProductLine | GSCRPT |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 7 Business Days |