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Cell Signaling Hsp60 (D6f1) Xp Rabbit mAb (Hrp Conjugate)
Cell Signaling Hsp60 (D6f1) Xp Rabbit mAb (Hrp Conjugate) - CSIG (Additional S&H or Hazmat Fees May Apply)
List Price
$435.00
Your Price
$435.00
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| NETA PART: | CSIG-46611S |
| MFG.PART: | 46611S |
| UNSPSC: | 41116012 |
| Manufacturer: | Cell Signaling |
| Size | 100 µl |
| Reactivity | H M R Hm Mk X Z B Pg |
| Sensitivity | Endogenous |
| Molecular Weight (kDa) | 60 |
| Source/Isotype | Rabbit IgG |
| Application/Dilution | {Western Blotting: 1:1000} |
| Storage | Supplied in 136 mM NaCl, 2.6 mM KCl, 12 mM sodium phosphate (pH 7.4) dibasic, 2 mg/ml BSA, and 50% glycerol. Store at –20°C. Do not aliquot the antibody. |
| Specificity/Sensitivity | HSP60 (D6F1) XP® Rabbit mAb (HRP Conjugate) recognizes endogenous levels of total HSP60 protein. |
| Species Reactivity | Human, Mouse, Rat, Hamster, Monkey, Xenopus, Zebrafish, Bovine, Pig |
| Source/Purification | Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Trp68 of human HSP60 protein. |
| Background | In both prokaryotic and eukaryotic cells the misfolding and aggregation of proteins during biogenesis and under conditions of cellular stress are prevented by molecular chaperones (1-3). HSP60 has primarily been known as a mitochondrial protein that is important for folding key proteins after import into the mitochondria (4). Research studies have shown that a significant amount of HSP60 is also present in the cytosol of many cells, and that it is induced by stress, inflammatory and immune responses, and autoantibodies correlated with Alzheimers, coronary artery diseases, MS, and diabetes (5-8). |
| SKU | CSIG-46611S |
|---|---|
| Supplier Part Number | 46611S |
| UM | UNIT |
| UNSPSC | 41116012 |
| Manufacturer | Cell Signaling |
| MSDS URL | https://www.cellsignal.com/contents/technical/safety-data-sheet-(sds)/resources-safety-data-sheets |
| Temperature | -20C |
| ProductLine | CSIG |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 5 Business Days |