Beckman Cd7-Ecd, 8h8.1, 1 Ml, Asr

Beckman the cd7 antigen is a membrane-embedded glycoprotein with a molecular weight of 40 kda. it is expressed at an early stage of t lineage ontogeny, during the extrathymic prothymocytic formation. cd7 expression persists throughout t lymphocytes differentiation defining cd7 as a pan-t marker. it is also expressed on thymocytes, on the majority of resting t lymphocytes, and natural killer cells (nk), and on a subset of pre-b lymphocytes and b lymphocytes from foetal bone marrow. cd7 expression is also detected on pluripotent hematopoietic stem cells. mature b-lymphocytes, cells from erythroid, myeloid and megacaryocytic lineage do not express the cd7 molecule. the cd7 molecule is involved in t lymphocytes activation. its expression may be quantitatively up-regulated on stimulated t lymphocytes. - BKMPFZ (Additional S&H Or Hazmat Fees May Apply)