Beckman Igd-Pe, Ia6-2, 50 Tests, Ruo

Beckman igd, a member of the immunoglobulin (ig) family, is expressed in naã¯ve b cells. it exists in a transmembrane and a soluble form. igd is, together with igm, the first antibody isotypes expressed during b cell ontogeny. bone marrow b cell precursors acquire surface igm after assembling heavy (h) and light (l) chain variable region exons from prototypic variable (v), diversity (d) and joining (j) gene segments through an antigen-independent process. after leaving the bone marrow to colonize secondary lymphoid organs, b cells acquire surface igd of the same specificity as surface igm through alternative splicing of a pre-messenger rna comprising v(d)j and both heavy chain constant μ (cμ) and cδ exons. - BKMPFZ (Additional S&H Or Hazmat Fees May Apply)