Beckman Cd13-Pe, Sj1d1, 2 Ml, Asr

Beckman the cd13 antigen is a transmembrane glycoprotein with a large extracellular region and a small intracellular nh2-terminal tail. it has a molecular weight of 150 kda and is expressed on the cell surface as a non-covalently linked homodimer. it is found on most cells of myeloid origin including neutrophils, eosinophils, basophils and monocytes from normal peripheral blood. it is absent from b and t lymphocytes as well as from red blood cells and platelets. this molecule is found on the surface of committed progenitor cells defined as the granulocyte-monocyte colony forming units (cfu-gm) in normal bone marrow. there are up to five subpopulations of cd13 molecules possessing different levels of glycosylation, which may explain the different binding patterns of various cd13 antibodies. - BKMPFZ (Additional S&H Or Hazmat Fees May Apply)