Beckman Il-4-Pe, 4d9, 2 Ml, Asr

Beckman interleukin-4 (il-4) is a monomeric 20 kda predominantly produced by activated t lymphocytes of the th2 phenotype, by mast cells and by some antigen-presenting cells. together with il-2, il-4 is an autocrine growth factor for activated t cells and for cytotoxic t cell precursors. il-4 is a major factor involved in the activation of resting b lymphocytes. together with il-13, il-4 induces isotype switch towards ige and igg1 isotypes. activated cd4+ t cells of the th1 phenotype produce predominantly il-2 and interferon γ, whereas cd4+ t cells of the th2 phenotype produce il-4, il-5, il6 and il-10. - BKMPFZ (Additional S&H Or Hazmat Fees May Apply)