Beckman Cd10-Ecd, Alb1, 1 Ml, Asr

Beckman the cd10 antigen is referred to as the common acute lymphoblastic leukemia antigen (calla). it is a type ii integral membrane protein of 100 kda, identified as the human membrane-associated neutral endopeptidase (ec3.4.24.11). it is expressed on uncommitted lymphoid precursors. cd10 expression is lost as cells enter the t lineage. in the b lineage, cd10 expression is lost later in ontogeny, as cells acquire surface ig expression. it is also expressed on activated and proliferating b cells in the germinal center, and on neutrophils as well as on bone marrow stromal cells. it is also expressed on a number of other cells of epithelial origin. - BKMPFZ (Additional S&H Or Hazmat Fees May Apply)