Genscript GenCRISPR™Ultra NLS-Cas9-GMP

Genscript GenCRISPR™ Ultra NLS-Cas9 is utilized for CRISPR gene editing applications. The Cas9 nuclease forms a stable ribonucleoprotein (RNP) complex with the guide RNA (gRNA) component. With the help of nuclear localization signal (NLS) expressed with the Cas9 nuclease, theRNP complex enters the nucleus and cleaves the target gene. When compared with a plasmid-based delivery system, the RNP delivery system has been observed to increase the on-target gene editing efficiency and decrease off-target effects. - GSCRPT (Additional S&H or Hazmat Fees May Apply)